CACNG6

Across TCGA cell cohorts, CACNG6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,373 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CACNG6-associated GO terms across cancer lineages are Positive regulation of mismatch repair, Acrosomal vesicle exocytosis, and Regulation of complement-dependent cytotoxicity. Each is linked with CACNG6 in more than 6 cancer types. Because this analysis shows association rather than direction, both CACNG6-to-partner and partner-to-CACNG6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mismatch repair grouped by CACNG6-low versus CACNG6-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG6→partner) and Y-score (partner→CACNG6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of mismatch repair →	-0.103	-1.812	<.001	<.001	3	7
LARGE_INTESTINE	Acrosomal vesicle exocytosis →	-0.760	-0.555	<.001	.008	3	7
CNS	Regulation of complement-dependent cytotoxicity →	+0.131	+0.438	<.001	.006	3	6
BONE	Cytoplasmic translation →	+0.065	+0.674	<.001	.009	3	6
SKIN	Negative regulation of complement-dependent cytotoxicity →	+0.188	+0.474	<.001	.006	3	6
SKIN	Negative regulation of activation of membrane attack complex →	+0.168	+0.471	<.001	.006	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,373 associations by consensus.

Positive regulation of mismatch repair by CACNG6 expression — PANCREAS

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