CACNG5

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CACNG5 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CACNG5 data layer compared with 21 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CACNG5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CACNG5 expression acts as an unfavorable survival marker.

LUAD, PDAC, and GBM are the cancer types where CACNG5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADOSTertileAll0.5710.937.00129view →
PDACDFSQuartileII,III,IV0.5680.958.0147view →
GBMDFSMedianAll0.2900.441.0173view →
LSCCOSMedianII,III,IV0.9471.000.0451view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CACNG5–LUAD (OS)

Kaplan–Meier survival curve for CACNG5 mass-spec protein-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration