CACNG5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CACNG5 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CACNG5-associated genes across cancer lineages are MYOG, KIF2B, and HTR1E. Each is linked with CACNG5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNG5-to-partner and partner-to-CACNG5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYOG grouped by CACNG5-low versus CACNG5-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNG5→partner) and Y-score (partner→CACNG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaMYOG →+0.029+5.209<.001.00531
SOFT_TISSUEKIF2B →+0.084+4.977<.001.00231
SOFT_TISSUEHTR1E →+0.167+4.369<.001.00831
SOFT_TISSUECCR8 →+0.016+4.369<.001.00831
SOFT_TISSUEENPP7 →+0.004+4.369<.001.00831
SOFT_TISSUEPRR23A →+0.077+4.882<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

MYOG by CACNG5 expression — BLOOD_Lymphoma

Box plot of MYOG in CACNG5-low vs CACNG5-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration