CACNB2

Across TCGA cell cohorts, CACNB2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,866 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CACNB2-associated GO terms across cancer lineages are Subtelomeric heterochromatin formation, Regulation of double-strand break repair, and Spliceosomal complex assembly. Each is linked with CACNB2 in more than 14 cancer types. Because this analysis shows association rather than direction, both CACNB2-to-partner and partner-to-CACNB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Subtelomeric heterochromatin formation grouped by CACNB2-low versus CACNB2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB2→partner) and Y-score (partner→CACNB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Subtelomeric heterochromatin formation →	+0.131	+0.485	<.001	<.001	3	15
BONE	Regulation of double-strand break repair →	+0.077	+1.837	<.001	<.001	3	13
BLOOD_Leukemia	Spliceosomal complex assembly →	+0.087	+0.621	<.001	<.001	3	13
BONE	Positive regulation of double-strand break repair →	+0.081	+2.150	<.001	<.001	3	12
BONE	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.192	+2.261	<.001	<.001	3	12
BONE	Positive regulation of DNA repair →	+0.076	+1.706	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,866 associations by consensus.

Subtelomeric heterochromatin formation by CACNB2 expression — BREAST

Explore this box plot interactively →