CACNB1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CACNB1 protein abundance is significantly associated with the RNA expression of many other genes, with 4,463 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CACNB1-associated genes across cancer lineages are NEFH, GALNT16, and SLC8A3. Each is linked with CACNB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNB1-to-partner and partner-to-CACNB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNB1 versus NEFH in GBM, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB1→partner) and Y-score (partner→CACNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMNEFH →+0.904+0.616<.001<.00132
GBMGALNT16 →+0.679+0.648.001.00132
GBMSLC8A3 →+1.050+0.517.007.00332
HNSCEEF1A2 →+2.161+1.001<.001<.00132
HNSCMYOM1 →+2.322+1.368<.001<.00132
GBMHHATL →+1.245+0.687<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,463 associations by consensus.

CACNB1 vs NEFH — GBM

Per-sample scatter of CACNB1 vs NEFH in GBM (Pearson r = 0.48).

Explore this scatter interactively →

Exploration