CACNB1

Across TCGA cell cohorts, CACNB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,655 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CACNB1-associated GO terms across cancer lineages are mRNA splice site recognition, Microtubule nucleation, and Microtubule polymerization or depolymerization. Each is linked with CACNB1 in more than 12 cancer types. Because this analysis shows association rather than direction, both CACNB1-to-partner and partner-to-CACNB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA splice site recognition grouped by CACNB1-low versus CACNB1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB1→partner) and Y-score (partner→CACNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	mRNA splice site recognition →	+0.106	+0.777	<.001	<.001	3	13
URINARY_TRACT	Microtubule nucleation →	+0.123	+1.524	<.001	<.001	3	13
STOMACH	Microtubule polymerization or depolymerization →	+0.115	+1.120	<.001	.009	3	12
LARGE_INTESTINE	Microtubule polymerization →	+0.116	+1.051	<.001	<.001	3	12
BLOOD_Leukemia	Negative regulation of binding →	+0.112	+1.865	<.001	<.001	3	12
URINARY_TRACT	DNA topological change →	+0.115	+1.397	.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,655 associations by consensus.

mRNA splice site recognition by CACNB1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →