CACNB1

Across TCGA cell cohorts, CACNB1 mutation is significantly associated with the RNA expression of many other genes, with 41 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CACNB1-associated genes across cancer lineages are C7, SLITRK3, and MMP24. Each is linked with CACNB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNB1-to-partner and partner-to-CACNB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C7 grouped by CACNB1-low versus CACNB1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNB1→partner) and Y-score (partner→CACNB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C7 →	+0.261	+2.829	.001	.005	3	1
BLOOD_Leukemia	SLITRK3 →	+0.020	+2.967	<.001	.003	3	1
BLOOD_Leukemia	MMP24 →	+0.122	+3.328	.006	.009	3	1
BLOOD_Leukemia	BTBD16 →	+0.048	+3.181	.004	.001	3	1
BLOOD_Leukemia	SYT14 →	+0.018	+3.947	.004	.005	3	1
BLOOD_Leukemia	NPFFR1 →	+0.008	+3.037	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

C7 by CACNB1 expression — BLOOD_Leukemia

Explore this box plot interactively →