CACNA2D3

Across TCGA patient cohorts, CACNA2D3 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,559 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CACNA2D3-associated proteins across cancer lineages are OGFR, TRIM2, and CRMP1. Each is linked with CACNA2D3 in more than 4 cancer types. Because this analysis shows association rather than direction, both CACNA2D3-to-partner and partner-to-CACNA2D3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNA2D3 versus OGFR in HNSC, with a Pearson correlation of -0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA2D3→partner) and Y-score (partner→CACNA2D3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OGFR →	-0.201	-0.634	<.001	.001	3	5
LSCC	TRIM2 →	+0.566	+1.087	<.001	<.001	3	5
LSCC	CRMP1 →	+0.577	+0.824	<.001	<.001	3	5
LUAD	LARP4 →	-0.299	-0.459	<.001	<.001	3	5
BRCA	DDX18 →	-0.446	-0.706	<.001	.001	3	5
BRCA	TBL3 →	-0.354	-0.682	<.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,559 associations by consensus.

CACNA2D3 vs OGFR — HNSC

Explore this scatter interactively →