CACNA2D2

Across TCGA patient cohorts, CACNA2D2 RNA expression is significantly associated with the protein abundance of many other proteins, with 21,334 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CACNA2D2-associated proteins across cancer lineages are PURA, RPS2, and SEPTIN4. Each is linked with CACNA2D2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CACNA2D2-to-partner and partner-to-CACNA2D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNA2D2 versus PURA in BRCA, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA2D2→partner) and Y-score (partner→CACNA2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PURA →	+0.442	+1.285	<.001	<.001	3	6
HNSC	RPS2 →	-0.257	-0.456	<.001	.004	3	6
PDAC	SEPTIN4 →	+0.514	+0.492	<.001	<.001	3	6
BRCA	DDAH1 →	+0.760	+1.135	<.001	<.001	3	6
BRCA	HDGFL3 →	+0.711	+1.258	<.001	<.001	3	6
CCRCC	KANK2 →	+0.480	+0.260	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,334 associations by consensus.

CACNA2D2 vs PURA — BRCA

Explore this scatter interactively →