CACNA2D2

Across TCGA patient cohorts, CACNA2D2 protein abundance is significantly associated with the RNA expression of many other genes, with 21,128 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CACNA2D2-associated genes across cancer lineages are GALNT16, ASPA, and TUBA1C. Each is linked with CACNA2D2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CACNA2D2-to-partner and partner-to-CACNA2D2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNA2D2 versus GALNT16 in BRCA, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA2D2→partner) and Y-score (partner→CACNA2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GALNT16 →	+0.744	+0.628	.004	.001	3	6
GBM	ASPA →	+1.085	+0.673	<.001	<.001	3	6
BRCA	TUBA1C →	-0.896	-1.126	<.001	<.001	3	6
LSCC	ABCA3 →	+2.059	+0.635	<.001	<.001	3	6
GBM	SLC8A3 →	+1.036	+0.564	<.001	<.001	2	6
HNSC	CHRDL1 →	+1.946	+0.842	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,128 associations by consensus.

CACNA2D2 vs GALNT16 — BRCA

Explore this scatter interactively →