CACNA2D2

Across TCGA cell cohorts, CACNA2D2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,588 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CACNA2D2-associated GO terms across cancer lineages are Regulation of potassium ion transport, Positive regulation of monoatomic ion transport, and Positive regulation of long-term synaptic potentiation. Each is linked with CACNA2D2 in more than 11 cancer types. Because this analysis shows association rather than direction, both CACNA2D2-to-partner and partner-to-CACNA2D2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of potassium ion transport grouped by CACNA2D2-low versus CACNA2D2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA2D2→partner) and Y-score (partner→CACNA2D2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of potassium ion transport →	-0.128	-0.823	.002	.009	3	12
BONE	Positive regulation of monoatomic ion transport →	-0.195	-0.979	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Positive regulation of long-term synaptic potentiation →	-0.137	-0.340	<.001	.006	3	11
BONE	Positive regulation of monoatomic ion transmembrane transport →	-0.145	-0.872	<.001	.002	3	11
BONE	Positive regulation of DNA repair →	+0.074	+0.714	<.001	.001	3	11
OESOPHAGUS	Regulation of macroautophagy →	+0.083	+1.052	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,588 associations by consensus.

Regulation of potassium ion transport by CACNA2D2 expression — OESOPHAGUS

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