Across TCGA pan-cancer cohorts, CACNA2D1-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CACNA2D1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CACNA2D1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CACNA2D1-AS1 is over-expressed in tumor.

LUAD, LUSC, and HNSC are the cancer types where CACNA2D1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CACNA2D1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	II,III,IV	+0.062	.005	4	view →
LUSC	All	All	+0.079	.041	1	view →
HNSC	All	II,III,IV	+0.010	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: CACNA2D1-AS1 RNA expression & survival · all CACNA2D1-AS1 data types