Across TCGA patient cohorts, CACNA1H mutation is significantly associated with the total protein of many other genes, with 69 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACNA1H-associated genes across cancer lineages are Caspase-7-cleavedD198, eIF4E, and eEF2. Each is linked with CACNA1H in more than 4 cancer types. Because this analysis shows association rather than direction, both CACNA1H-to-partner and partner-to-CACNA1H results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1H→partner) and Y-score (partner→CACNA1H) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.723	+1.745	.003	.004	3	5
STAD	eIF4E →	+0.150	+3.190	.030	.008	3	3
BLCA	eEF2 →	+0.381	+3.017	.003	.019	3	3
UCEC	GAPDH →	+0.373	+1.777	.009	.001	3	3
UCEC	IGFBP2 →	-0.413	-1.502	.017	.025	3	3
UCEC	PCNA →	+0.272	+1.669	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 69 associations by consensus.

Exploration

CACNA1H survival (RNA) · tumor vs normal (RNA) · all CACNA1H data types