CACNA1G

Across TCGA patient cohorts, CACNA1G mutation is significantly associated with the total protein of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACNA1G-associated genes across cancer lineages are STAT3_pY705, TIGAR, and Tuberin. Each is linked with CACNA1G in more than 3 cancer types. Because this analysis shows association rather than direction, both CACNA1G-to-partner and partner-to-CACNA1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by CACNA1G-low versus CACNA1G-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1G→partner) and Y-score (partner→CACNA1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.218	-1.222	.002	.029	3	4
LUSC	TIGAR →	+0.131	+3.183	.038	.009	2	4
LUSC	Tuberin →	-0.302	-2.312	.035	.035	3	3
COAD	eEF2 →	+0.269	+2.321	.014	.033	3	3
UCEC	MEK1 →	+0.201	+1.584	.044	.004	3	3
COAD	PCNA →	+0.277	+2.472	.002	.010	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

STAT3_pY705 by CACNA1G expression — UCEC

Explore this box plot interactively →