CACNA1G

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CACNA1G mutation is significantly associated with the RNA expression of many other genes, with 941 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CACNA1G-associated genes across cancer lineages are ODF1, FGF4, and TXNDC8. Each is linked with CACNA1G in more than 3 cancer types. Because this analysis shows association rather than direction, both CACNA1G-to-partner and partner-to-CACNA1G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ODF1 grouped by CACNA1G-low versus CACNA1G-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1G→partner) and Y-score (partner→CACNA1G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaODF1 →+0.035+1.944.002.00134
SOFT_TISSUEFGF4 →+0.024+4.417<.001.00433
URINARY_TRACTTXNDC8 →+0.010+4.087<.001.00932
BLOOD_LymphomaC18orf63 →+0.011+4.282<.001<.00132
LUNG_NSCLC_LUSCASZ1 →+0.089+4.108.008.00532
BLOOD_LymphomaPIP →+0.105+3.165<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 941 associations by consensus.

ODF1 by CACNA1G expression — BLOOD_Leukemia

Box plot of ODF1 in CACNA1G-low vs CACNA1G-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration