CACNA1F

Across TCGA pan-cancer cohorts, CACNA1F Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CACNA1F data layer compared with 22 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher CACNA1F Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CACNA1F expression acts as an unfavorable survival marker, although some lineages such as COAD show a favorable association.

DLBC, LIHC, and UCEC are the cancer types where CACNA1F Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Median	II,III,IV	0.172	0.949	<.001	27	view →
LIHC	OS	Median	All	0.279	0.780	<.001	21	view →
UCEC	OS	Median	IV	0.275	0.637	.008	12	view →
LGG	DFS	Median	All	0.110	0.826	<.001	3	view →
ACC	OS	Median	All	0.149	0.686	.047	3	view →
SCLC	DFS	Median	II,III,IV	0.274	0.615	.047	3	view →
COAD	DFS	Median	II,III,IV	0.926	0.742	.017	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CACNA1F–DLBC (OS)

Open the DLBC breakdown →