CACNA1D

Across TCGA patient cohorts, CACNA1D RNA expression is significantly associated with the protein abundance of many other proteins, with 20,038 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CACNA1D-associated proteins across cancer lineages are SORBS2, CHDH, and DDAH1. Each is linked with CACNA1D in more than 5 cancer types. Because this analysis shows association rather than direction, both CACNA1D-to-partner and partner-to-CACNA1D results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNA1D versus SORBS2 in HNSC, with a Pearson correlation of 0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1D→partner) and Y-score (partner→CACNA1D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SORBS2 →	+0.566	+0.491	<.001	.003	3	6
UCEC	CHDH →	+0.570	+1.058	<.001	<.001	3	6
BRCA	DDAH1 →	+0.808	+1.448	<.001	<.001	3	6
BRCA	USP10_S547 →	-0.709	-1.353	<.001	<.001	3	6
HNSC	UTRN →	+0.331	+0.646	<.001	<.001	3	6
BRCA	REEP4_S152 →	-0.534	-1.011	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,038 associations by consensus.

CACNA1D vs SORBS2 — HNSC

Explore this scatter interactively →