CACNA1A

Across TCGA patient cohorts, CACNA1A RNA expression is significantly associated with the go_rna of many other GO terms, with 7,161 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CACNA1A-associated GO terms across cancer lineages are Negative regulation of cell growth, Protein stabilization, and Regulation of protein localization to cilium. Each is linked with CACNA1A in more than 21 cancer types. Because this analysis shows association rather than direction, both CACNA1A-to-partner and partner-to-CACNA1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell growth grouped by CACNA1A-low versus CACNA1A-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1A→partner) and Y-score (partner→CACNA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of cell growth →	+0.054	+0.445	<.001	<.001	3	22
STAD	Protein stabilization →	+0.060	+0.469	<.001	<.001	3	22
STAD	Regulation of protein localization to cilium →	+0.038	+0.370	<.001	<.001	3	21
STAD	Protein folding →	+0.055	+0.394	<.001	<.001	3	21
STAD	Positive regulation of DNA-templated transcription, elongation →	+0.053	+0.396	<.001	<.001	3	21
STAD	Regulation of calcium ion export across plasma membrane →	+0.051	+0.423	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,161 associations by consensus.

Negative regulation of cell growth by CACNA1A expression — STAD

Explore this box plot interactively →