CACNA1A

Across TCGA patient cohorts, CACNA1A protein abundance is significantly associated with the protein abundance of many other proteins, with 11,753 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CACNA1A-associated proteins across cancer lineages are ACIN1_S384, ARPC5L, and ARPC5L_S64. Each is linked with CACNA1A in more than 1 cancer types. Because this analysis shows association rather than direction, both CACNA1A-to-partner and partner-to-CACNA1A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CACNA1A versus ACIN1_S384 in GBM, with a Pearson correlation of -0.36.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CACNA1A→partner) and Y-score (partner→CACNA1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACIN1_S384 →	-0.454	-0.321	<.001	.006	3	1
GBM	ARPC5L →	+0.245	+0.590	<.001	<.001	3	1
GBM	ARPC5L_S64 →	+0.582	+0.526	<.001	<.001	3	1
GBM	ACIN1_S410 →	-0.305	-0.359	<.001	<.001	3	1
GBM	ARPP21 →	+0.770	+0.497	<.001	<.001	3	1
GBM	ARPP21_S138 →	+0.774	+0.480	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,753 associations by consensus.

CACNA1A vs ACIN1_S384 — GBM

Explore this scatter interactively →