CACHD1

Across TCGA cell cohorts, CACHD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,718 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CACHD1-associated GO terms across cancer lineages are RNA export from nucleus, mRNA transport, and Protein-DNA complex organization. Each is linked with CACHD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CACHD1-to-partner and partner-to-CACHD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA export from nucleus grouped by CACHD1-low versus CACHD1-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CACHD1→partner) and Y-score (partner→CACHD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	RNA export from nucleus →	+0.135	+1.884	<.001	.001	3	12
OESOPHAGUS	mRNA transport →	+0.118	+1.274	.001	.001	3	12
BONE	Protein-DNA complex organization →	+0.077	+1.932	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Heterochromatin formation →	+0.073	+1.498	<.001	<.001	3	11
BONE	Transcription initiation at RNA polymerase II promoter →	+0.089	+1.935	<.001	<.001	3	11
OESOPHAGUS	Nucleic acid transport →	+0.107	+1.309	<.001	.005	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,718 associations by consensus.

RNA export from nucleus by CACHD1 expression — BONE

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