CACFD1

Across TCGA patient cohorts, CACFD1 mutation is significantly associated with the RNA expression of many other genes, with 381 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CACFD1-associated genes across cancer lineages are NF1P10, IGHV2-70, and LINC02340. Each is linked with CACFD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACFD1-to-partner and partner-to-CACFD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NF1P10 grouped by CACFD1-low versus CACFD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACFD1→partner) and Y-score (partner→CACFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NF1P10 →	+0.124	+2.456	.007	.002	3	2
UCEC	IGHV2-70 →	+1.487	+3.329	.006	.005	3	1
UCEC	LINC02340 →	+0.362	+2.882	.002	.001	3	1
UCEC	MIR8082 →	+0.322	+2.424	.001	.005	3	1
UCEC	TRBV12-4 →	+0.541	+3.337	.003	.005	3	1
UCEC	MIR8071-2 →	+0.977	+2.196	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 381 associations by consensus.

NF1P10 by CACFD1 expression — UCEC

Explore this box plot interactively →