CACFD1

Across TCGA cell cohorts, CACFD1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CACFD1-associated genes across cancer lineages are DMRTC2, TSHB, and HTR1E. Each is linked with CACFD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CACFD1-to-partner and partner-to-CACFD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DMRTC2 grouped by CACFD1-low versus CACFD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CACFD1→partner) and Y-score (partner→CACFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	DMRTC2 →	+0.049	+5.539	<.001	.003	3	1
BLOOD_Lymphoma	TSHB →	+0.092	+5.643	<.001	.002	3	1
SKIN	HTR1E →	+0.036	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

DMRTC2 by CACFD1 expression — BLOOD_Leukemia

Explore this box plot interactively →