CABS1

Across TCGA pan-cancer cohorts, CABS1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CABS1 data layer compared with 16 for mass-spec protein.

The strongest signal is observed in brain lower grade glioma (LGG), where higher CABS1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CABS1 expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

LGG, LUAD, and GBM are the cancer types where CABS1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.516	0.833	.008	12	view →
LUAD	OS	Median	All	0.415	0.707	.004	10	view →
GBM	OS	Median	All	0.176	0.417	.045	3	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →
STAD	DFS	Median	II,III,IV	0.849	0.325	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CABS1–LGG (DFS)

Open the LGG breakdown →