CABP7

Across TCGA patient cohorts, CABP7 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CABP7-associated genes across cancer lineages are ERK2, Ku80, and MEK1. Each is linked with CABP7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CABP7-to-partner and partner-to-CABP7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ERK2 grouped by CABP7-low versus CABP7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABP7→partner) and Y-score (partner→CABP7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ERK2 →	+0.216	+3.321	.032	.010	3	1
UCEC	Ku80 →	+0.362	+3.335	.003	.005	3	1
UCEC	MEK1 →	+0.506	+3.321	.008	.010	3	1
UCEC	VEGFR2 →	+0.399	+2.817	.010	.036	3	1
UCEC	p62 Lck ligand →	+0.669	+3.321	<.001	.010	2	1
UCEC	TIGAR →	+0.187	+2.196	.019	.034	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

ERK2 by CABP7 expression — UCEC

Explore this box plot interactively →