Across TCGA pan-cancer cohorts, CABP5 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CABP5’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where CABP5 RNA is repressed in tumor relative to normal tissue. In most cancer types CABP5 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.
LUSC, LUAD, and BRCA are the cancer types where CABP5 tumor–normal differential expression is most reproducible.