CABP4

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CABP4 mutation is significantly associated with the total protein of many other genes, with 25 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CABP4-associated genes across cancer lineages are TFRC, HER2_pY1248, and PDCD4. Each is linked with CABP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CABP4-to-partner and partner-to-CABP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by CABP4-low versus CABP4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABP4→partner) and Y-score (partner→CABP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMTFRC →+0.869+2.321.001.03332
SKCMHER2_pY1248 →-0.147-2.309.035.03332
SKCMPDCD4 →-0.585-3.584.002.00223
SKCMCyclin-B1 →+0.502+2.182.010.03332
UCECACC_pS79 →+0.403+3.000.044.03731
UCECCD31 →-0.260-3.000.002.03731
Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

TFRC by CABP4 expression — SKCM

Box plot of TFRC in CABP4-low vs CABP4-high samples in SKCM.

Explore this box plot interactively →

Exploration