CABP1

Across TCGA patient cohorts, CABP1 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CABP1-associated genes across cancer lineages are TFRC, ASNS, and Caspase-7-cleavedD198. Each is linked with CABP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CABP1-to-partner and partner-to-CABP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by CABP1-low versus CABP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABP1→partner) and Y-score (partner→CABP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TFRC →	+0.777	+2.459	.002	.020	3	2
UCEC	ASNS →	+0.617	+3.169	<.001	.019	3	2
UCEC	Caspase-7-cleavedD198 →	+0.583	+2.827	.042	.035	3	2
UCEC	Cyclin-B1 →	+0.875	+3.169	.001	.018	3	2
UCEC	PRAS40_pT246 →	+0.188	+3.169	.023	.019	3	1
UCEC	Rad50 →	-0.311	-3.321	.007	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

TFRC by CABP1 expression — UCEC

Explore this box plot interactively →