CABLES2

Across TCGA patient cohorts, CABLES2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,900 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CABLES2-associated genes across cancer lineages are FAM167A, SRIP3, and NIFKP4. Each is linked with CABLES2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CABLES2-to-partner and partner-to-CABLES2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CABLES2 versus FAM167A in OV, with a Pearson correlation of -0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CABLES2→partner) and Y-score (partner→CABLES2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAM167A →	-1.905	-0.728	<.001	.006	3	2
OV	SRIP3 →	+1.187	+1.024	.007	.007	3	2
OV	NIFKP4 →	+0.132	+0.864	<.001	<.001	3	2
BRCA	SPDEF →	-2.327	-0.405	.003	<.001	3	2
BRCA	ZG16B →	-1.852	-0.306	<.001	.003	3	2
BRCA	ANTXR1 →	-1.048	-0.431	.009	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,900 associations by consensus.

CABLES2 vs FAM167A — OV

Explore this scatter interactively →