CABLES2

Across TCGA cell cohorts, CABLES2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,367 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CABLES2-associated GO terms across cancer lineages are Cytoskeleton-dependent cytokinesis, Establishment of spindle orientation, and Positive regulation of mitotic cytokinesis. Each is linked with CABLES2 in more than 13 cancer types. Because this analysis shows association rather than direction, both CABLES2-to-partner and partner-to-CABLES2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoskeleton-dependent cytokinesis grouped by CABLES2-low versus CABLES2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CABLES2→partner) and Y-score (partner→CABLES2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cytoskeleton-dependent cytokinesis →	+0.085	+1.269	<.001	<.001	3	14
CNS	Establishment of spindle orientation →	+0.085	+0.893	<.001	<.001	3	14
SOFT_TISSUE	Positive regulation of mitotic cytokinesis →	+0.135	+0.898	<.001	<.001	3	13
KIDNEY	Regulation of nucleotide-excision repair →	+0.113	+0.617	<.001	.001	3	13
LUNG_SCLC	Cell division →	+0.075	+0.800	<.001	.008	3	13
LUNG_SCLC	Cytokinesis →	+0.073	+0.822	<.001	.006	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,367 associations by consensus.

Cytoskeleton-dependent cytokinesis by CABLES2 expression — STOMACH

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