CABLES1

Across TCGA cell cohorts, CABLES1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,210 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CABLES1-associated GO terms across cancer lineages are Negative regulation of glial cell migration, Negative regulation of interleukin-5 production, and Positive regulation of cell proliferation involved in heart morphogenesis. Each is linked with CABLES1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CABLES1-to-partner and partner-to-CABLES1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of glial cell migration grouped by CABLES1-low versus CABLES1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CABLES1→partner) and Y-score (partner→CABLES1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Negative regulation of glial cell migration →	+0.151	+1.084	.004	.003	3	8
SOFT_TISSUE	Negative regulation of interleukin-5 production →	+0.858	+1.666	.002	<.001	3	7
BLOOD_Lymphoma	Positive regulation of cell proliferation involved in heart morphogenesis →	+0.106	+1.538	.001	.003	3	7
STOMACH	Actin filament bundle organization →	+0.085	+1.526	<.001	.002	3	6
OVARY	Cellular response to calcium ion starvation →	+0.136	+0.973	.001	.002	3	6
CNS	Actin filament network formation →	+0.090	+0.766	.001	.005	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,210 associations by consensus.

Negative regulation of glial cell migration by CABLES1 expression — BREAST

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