CABIN1

Across TCGA pan-cancer cohorts, CABIN1 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CABIN1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CABIN1 mass-spec protein is repressed in tumor relative to normal tissue. In most cancer types CABIN1 is over-expressed in tumor, although a few such as LUAD and PDAC show the opposite, repressed pattern.

LUAD, CCRCC, and HNSC are the cancer types where CABIN1 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CABIN1 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	−0.116	<.001	7	view →
CCRCC	Male	All	+0.191	<.001	6	view →
HNSC	Male	IV	+0.131	.033	5	view →
PDAC	Male	II,III,IV	−0.290	.002	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

CABIN1–LUAD

Open the LUAD breakdown →