CA6

Across TCGA patient cohorts, CA6 protein abundance is significantly associated with the RNA expression of many other genes, with 2,476 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CA6-associated genes across cancer lineages are RAPGEF3, PTK6, and TRIB3. Each is linked with CA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CA6-to-partner and partner-to-CA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA6 versus RAPGEF3 in UCEC, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA6→partner) and Y-score (partner→CA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RAPGEF3 →	+1.617	+2.010	.004	.003	3	2
UCEC	PTK6 →	+2.996	+2.326	<.001	.007	3	1
UCEC	TRIB3 →	-1.386	-1.376	.003	.009	3	1
UCEC	MOSPD1 →	+0.973	+1.555	.005	.001	3	1
UCEC	PLA2G4C →	+0.679	+1.135	.006	<.001	3	1
UCEC	TFPI2 →	-1.433	-1.566	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,476 associations by consensus.

CA6 vs RAPGEF3 — UCEC

Explore this scatter interactively →