CA6

Across TCGA cell cohorts, CA6 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CA6-associated genes across cancer lineages are TMCO5A, OR10H5, and KRTAP17-1. Each is linked with CA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CA6-to-partner and partner-to-CA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMCO5A grouped by CA6-low versus CA6-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA6→partner) and Y-score (partner→CA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TMCO5A →	+0.097	+4.977	<.001	.007	3	1
SKIN	OR10H5 →	+0.019	+4.977	<.001	.007	3	1
SKIN	KRTAP17-1 →	+0.025	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

TMCO5A by CA6 expression — SKIN

Explore this box plot interactively →