Across TCGA pan-cancer cohorts, CA5BP1 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CA5BP1 data layer compared with 24 for mass-spec protein.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CA5BP1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CA5BP1 expression acts as an unfavorable survival marker.

HNSC, COAD, and UCEC are the cancer types where CA5BP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Median	All	0.087	0.710	<.001	36	view →
COAD	OS	Median	II,III,IV	0.140	0.855	<.001	27	view →
UCEC	OS	Median	II,III,IV	0.231	0.768	.010	24	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: CA5BP1 tumor-vs-normal RNA expression · all CA5BP1 data types