CA5B

Across TCGA pan-cancer cohorts, CA5B mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CA5B data layer compared with 21 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CA5B mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CA5B expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

LUAD, CCRCC, and PDAC are the cancer types where CA5B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Median	III,IV	0.544	0.936	.006	13	view →
CCRCC	DFS	Quartile	All	0.900	0.573	.020	4	view →
PDAC	DFS	Median	IV	0.959	0.409	.049	3	view →
LSCC	OS	Median	II,III,IV	0.879	1.000	.016	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CA5B–LUAD (DFS)

Open the LUAD breakdown →