CA5B

Across TCGA patient cohorts, CA5B RNA expression is significantly associated with the protein abundance of many other proteins, with 16,711 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CA5B-associated proteins across cancer lineages are SORBS3, CLPX, and FERMT2. Each is linked with CA5B in more than 5 cancer types. Because this analysis shows association rather than direction, both CA5B-to-partner and partner-to-CA5B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA5B versus SORBS3 in BRCA, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CA5B→partner) and Y-score (partner→CA5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SORBS3 →	+0.391	+0.607	<.001	<.001	3	6
LUAD	CLPX →	-0.274	-0.354	<.001	<.001	3	6
BRCA	FERMT2 →	+0.591	+0.521	<.001	<.001	3	6
BRCA	KANK2 →	+0.635	+0.659	<.001	<.001	3	6
BRCA	LUM →	+0.912	+0.593	<.001	<.001	3	6
LUAD	PRKRA_S18 →	+0.454	+0.329	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,711 associations by consensus.

CA5B vs SORBS3 — BRCA

Explore this scatter interactively →