CA5B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CA5B mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CA5B-associated genes across cancer lineages are LCE1F. Each is linked with CA5B in more than 1 cancer types. Because this analysis shows association rather than direction, both CA5B-to-partner and partner-to-CA5B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCE1F grouped by CA5B-low versus CA5B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA5B→partner) and Y-score (partner→CA5B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINELCE1F →+0.165+5.415<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

LCE1F by CA5B expression — LARGE_INTESTINE

Box plot of LCE1F in CA5B-low vs CA5B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration