CA5AP1

Across TCGA pan-cancer cohorts, CA5AP1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CA5AP1 data layer.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher CA5AP1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CA5AP1 expression acts as an unfavorable survival marker, although some lineages such as LGG and BLCA show a favorable association.

LUSC, ESCA, and HNSC are the cancer types where CA5AP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	IV	0.001	0.673	.014	45	view →
ESCA	DFS	Tertile	II,III,IV	0.378	0.577	.004	38	view →
HNSC	OS	Tertile	IV	0.261	0.543	.001	33	view →
LGG	DFS	Median	All	0.617	0.352	<.001	29	view →
BLCA	OS	Tertile	III,IV	0.826	0.525	.018	27	view →
LUAD	DFS	Tertile	II,III,IV	0.255	0.600	<.001	27	view →
DLBC	OS	Tertile	All	0.528	0.945	.010	26	view →
SKCM	DFS	Tertile	IV	0.165	0.661	.021	24	view →
KIRC	OS	Tertile	All	0.544	0.656	.009	18	view →
UCS	DFS	Tertile	IV	0.996	0.570	.039	18	view →
LAML	DFS	Tertile	All	0.708	0.438	.032	12	view →
PRAD	OS	Tertile	All	0.969	0.997	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

CA5AP1–LUSC (OS)

Open the LUSC breakdown →