CA4

Across TCGA patient cohorts, CA4 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,077 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CA4-associated proteins across cancer lineages are ARHGAP6, SHANK3, and KANK3_S160. Each is linked with CA4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CA4-to-partner and partner-to-CA4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA4 versus ARHGAP6 in UCEC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CA4→partner) and Y-score (partner→CA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARHGAP6 →	+0.513	+0.527	.001	.006	3	6
CCRCC	SHANK3 →	+0.506	+1.744	<.001	<.001	3	6
CCRCC	KANK3_S160 →	+0.928	+1.549	<.001	<.001	3	6
UCEC	ARHGAP24_S391 →	+0.449	+0.438	<.001	.001	3	6
CCRCC	PLVAP →	+0.756	+1.551	<.001	<.001	3	6
GBM	PYGM →	+0.772	+0.643	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,077 associations by consensus.

CA4 vs ARHGAP6 — UCEC

Explore this scatter interactively →