CA4

Across TCGA patient cohorts, CA4 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CA4-associated genes across cancer lineages are Adipocytes, Skeletal muscle, and CD4+ T-cells. Each is linked with CA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CA4-to-partner and partner-to-CA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Adipocytes grouped by CA4-low versus CA4-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA4→partner) and Y-score (partner→CA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Adipocytes →	+0.078	+1.915	<.001	.046	3	1
SKCM	Skeletal muscle →	+0.080	+3.006	<.001	.020	3	1
HNSC	CD4+ T-cells →	+0.010	+4.936	<.001	.047	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Adipocytes by CA4 expression — SKCM

Explore this box plot interactively →