CA4

Across TCGA cell cohorts, CA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 553 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible CA4-associated GO terms across cancer lineages are Determination of dorsal/ventral asymmetry, Negative regulation of dendrite development, and Negative regulation of epithelial cell migration. Each is linked with CA4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CA4-to-partner and partner-to-CA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Determination of dorsal/ventral asymmetry grouped by CA4-low versus CA4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CA4→partner) and Y-score (partner→CA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Determination of dorsal/ventral asymmetry →	-0.161	-0.212	.006	.009	3	5
SOFT_TISSUE	Negative regulation of dendrite development →	-0.140	-0.894	.003	.002	3	4
OVARY	Negative regulation of epithelial cell migration →	+0.080	+0.184	<.001	.005	2	5
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.051	+0.033	<.001	<.001	3	4
BONE	Nonassociative learning →	+1.230	+0.199	.001	.004	3	4
OVARY	Positive regulation of growth →	-0.034	-0.217	.002	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 553 associations by consensus.

Determination of dorsal/ventral asymmetry by CA4 expression — OVARY

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