CA3

Across TCGA patient cohorts, CA3 protein abundance is significantly associated with the RNA expression of many other genes, with 9,289 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CA3-associated genes across cancer lineages are CHRDL1, LYVE1, and KLF2. Each is linked with CA3 in more than 6 cancer types. Because this analysis shows association rather than direction, both CA3-to-partner and partner-to-CA3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA3 versus CHRDL1 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA3→partner) and Y-score (partner→CA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CHRDL1 →	+1.788	+1.093	<.001	.003	3	7
PDAC	LYVE1 →	+1.093	+0.626	<.001	<.001	3	7
OV	KLF2 →	+1.170	+1.020	<.001	<.001	3	6
OV	ADH1B →	+2.550	+1.089	<.001	<.001	3	6
CCRCC	PDE2A →	+0.858	+0.860	.003	<.001	3	6
OV	HBA2 →	+1.835	+1.011	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,289 associations by consensus.

CA3 vs CHRDL1 — OV

Explore this scatter interactively →