CA3

Across TCGA cell cohorts, CA3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,201 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CA3-associated GO terms across cancer lineages are Urate metabolic process, Sterol catabolic process, and Negative regulation of kinase activity. Each is linked with CA3 in more than 5 cancer types. Because this analysis shows association rather than direction, both CA3-to-partner and partner-to-CA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Urate metabolic process grouped by CA3-low versus CA3-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CA3→partner) and Y-score (partner→CA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Urate metabolic process →	-0.197	-0.167	<.001	<.001	3	6
LUNG_NSCLC_LUAD	Sterol catabolic process →	-0.235	-0.531	<.001	<.001	3	6
BLOOD_Leukemia	Negative regulation of kinase activity →	+0.045	+0.517	<.001	.004	3	6
LUNG_NSCLC_LUAD	Cholesterol catabolic process →	-0.235	-0.531	<.001	<.001	3	6
PANCREAS	Adenylate cyclase-activating G protein-coupled receptor signaling pathway →	-0.053	-0.576	.001	.009	3	6
BLOOD_Lymphoma	Regulation of ATPase-coupled calcium transmembrane transporter activity →	+0.127	+0.174	.005	.007	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,201 associations by consensus.

Urate metabolic process by CA3 expression — BLOOD_Lymphoma

Explore this box plot interactively →