CA2

Across TCGA patient cohorts, CA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,185 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CA2-associated proteins across cancer lineages are SART3, SLC9A1_S796, and AHNAK2_S5175. Each is linked with CA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CA2-to-partner and partner-to-CA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA2 versus SART3 in GBM, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CA2→partner) and Y-score (partner→CA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SART3 →	-0.323	-0.815	<.001	.002	3	5
PDAC	SLC9A1_S796 →	+0.625	+1.195	<.001	<.001	3	5
LSCC	AHNAK2_S5175 →	+0.756	+0.747	.005	.004	3	4
GBM	RBM10 →	-0.233	-0.634	<.001	<.001	3	4
HNSC	SERPINB1 →	+0.628	+1.948	<.001	<.001	3	4
GBM	SMC1A →	-0.272	-0.707	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,185 associations by consensus.

CA2 vs SART3 — GBM

Explore this scatter interactively →