CA2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CA2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,113 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible CA2-associated genes across cancer lineages are BABAM2, MCM9, and HADHB. Each is linked with CA2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CA2-to-partner and partner-to-CA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA2 versus BABAM2 in BLOOD_Lymphoma, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA2→partner) and Y-score (partner→CA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaBABAM2 →+1.852+4.080.002<.00135
UPPER_AERODIGESTIVE_TRACTMCM9 →+0.858+2.024.001<.00134
UPPER_AERODIGESTIVE_TRACTHADHB →+1.250+2.125<.001.00134
UPPER_AERODIGESTIVE_TRACTRAB1A →+0.521+1.598.003.00534
BLOOD_LymphomaIMPA2 →+2.292+3.258.003.00134
BLOOD_LeukemiaIMPACT →+2.529+3.282.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,113 associations by consensus.

CA2 vs BABAM2 — BLOOD_Lymphoma

Per-sample scatter of CA2 vs BABAM2 in BLOOD_Lymphoma (Pearson r = 0.83).

Explore this scatter interactively →

Exploration