Across TCGA pan-cancer cohorts, CA15P2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CA15P2’s most consistent transcriptional readouts.
The strongest signal is observed in esophageal carcinoma (ESCA), where CA15P2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CA15P2 is over-expressed in tumor.
ESCA and KIRC are the cancer types where CA15P2 tumor–normal differential expression is most reproducible.