CA14

Across TCGA patient cohorts, CA14 protein abundance is significantly associated with the RNA expression of many other genes, with 5,552 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CA14-associated genes across cancer lineages are TPTEP1, SGK2, and NDRG3. Each is linked with CA14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CA14-to-partner and partner-to-CA14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CA14 versus TPTEP1 in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA14→partner) and Y-score (partner→CA14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TPTEP1 →	+0.929	+0.545	.005	<.001	3	1
GBM	SGK2 →	+0.433	+0.344	.004	.008	3	1
GBM	NDRG3 →	+0.336	+0.355	<.001	.006	3	1
GBM	CDS2 →	+0.360	+0.465	<.001	<.001	3	1
GBM	CDH20 →	+0.719	+0.395	.007	.002	3	1
GBM	MYOM1 →	+0.708	+0.594	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,552 associations by consensus.

CA14 vs TPTEP1 — GBM

Explore this scatter interactively →