CA14

Across TCGA cell cohorts, CA14 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CA14-associated genes across cancer lineages are C6orf118, BTBD16, and FERD3L. Each is linked with CA14 in more than 1 cancer types. Because this analysis shows association rather than direction, both CA14-to-partner and partner-to-CA14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by CA14-low versus CA14-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA14→partner) and Y-score (partner→CA14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C6orf118 →	+0.045	+4.450	<.001	.001	3	1
BLOOD_Leukemia	BTBD16 →	+0.075	+3.959	<.001	.005	3	1
BLOOD_Leukemia	FERD3L →	+0.031	+4.384	<.001	.006	3	1
BLOOD_Leukemia	SMR3B →	+0.031	+4.507	<.001	.001	3	1
BLOOD_Leukemia	AMY1A →	+0.066	+3.705	<.001	.007	3	1
BLOOD_Leukemia	C1QTNF9 →	+0.040	+3.852	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

C6orf118 by CA14 expression — BLOOD_Leukemia

Explore this box plot interactively →