Across TCGA pan-cancer cohorts, CA13 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CA13 data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CA13 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CA13 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

LUAD, PDAC, and HNSC are the cancer types where CA13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	0.609	0.233	.013	12	view →
PDAC	OS	Tertile	All	0.955	0.780	.018	4	view →
HNSC	OS	Median	II,III,IV	0.952	1.000	.016	3	view →
LSCC	DFS	Quartile	All	0.624	0.882	.022	2	view →
CCRCC	OS	Tertile	All	0.760	0.891	.027	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: CA13 tumor-vs-normal RNA expression · all CA13 data types