Across TCGA patient cohorts, CA13 mutation is significantly associated with the total protein of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CA13-associated genes across cancer lineages are Rad50, VHL, and Caspase-7-cleavedD198. Each is linked with CA13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CA13-to-partner and partner-to-CA13 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CA13→partner) and Y-score (partner→CA13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Rad50 →	-0.248	-2.459	.034	.020	3	1
UCEC	VHL →	-0.928	-2.321	.004	.034	3	1
UCEC	Caspase-7-cleavedD198 →	+0.775	+3.189	.006	.010	2	1
UCEC	MEK1 →	+0.603	+3.584	<.001	.002	1	1
UCEC	Notch1 →	+0.205	+2.459	.002	.020	1	1
UCEC	p62 Lck ligand →	+0.425	+2.459	.006	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

CA13 survival (RNA) · tumor vs normal (RNA) · all CA13 data types